Our natural prejudgment of reality is against God. To receive the truth of God requires that our “anti” bias be changed. The key work of the Holy Spirit in regeneration is not giving new knowledge to the brain but changing the disposition of the heart. Before the Spirit turns that heart of stone into a heart of flesh, we have no desire for the things of God. We may desire the blessings that only God can give us, but we have no affection for the things of God. At the moment of regeneration, the eyes of the heart are opened somewhat, but this is just the beginning. The whole Christian life involves an unfolding and enlarging of the heart’s openness to the things of God.